Breath of Life Nitric Oxide Boosting Toothpaste
The world’s #1 rated Nitric Oxide Boosting toothpaste that boosts your body’s own nitric oxide.
Support your oral and systemic health with the world’s first nitric oxide–enhancing toothpaste. Free from fluoride and harsh toxins, Breath of Life supports your mouth’s natural nitric oxide production — nurturing the oral microbiome that links a healthy smile to a healthy heart. Developed by biomedical scientist Dr. Nathan S. Bryan, International Expert in Nitric Oxide Biochemistry.
Key Benefits May Support:
- Boosts your mouth’s natural microbiome
- Freshens breath naturally
- Remineralizes and strengthens enamel
- Fluoride-free formula, free of harsh toxins
- Enhances gum health and circulation
Maximum of 3 per order.
Not available for resell. For personal use only.
$24.99
Description
Healthier Gums. Brighter Smiles. More Confidence.
Your oral health thrives on strong circulation, healthy gums, a balanced microbiome, and optimal performance. But as you age, nitric oxide production declines - leading to weaker gum health, reduced blood flow, and a less vibrant smile. Conventional fluoride toothpastes and antiseptic mouthwashes make it worse by disrupting the very oral bacteria that produce nitric oxide.
That's why we created Breath of Life Nitric Oxide Boosting Toothpaste - a revolutionary formula designed to support the oral microbiome that boosts nitric oxide levels, improves circulation, and supports gum health, so you can enjoy a healthier smile every day.
"We have known for more than 100 years that poor oral hygiene leads to increased risk of cardiovascular disease. Today we know that the oral microbiome responsible for optimizing nitric oxide production accounts for the oral-systemic link. Stringent antiseptics, fluoride, and poor oral hygiene all disrupt the oral microbiome. Our nitric oxide-focused line of oral care supports the microbiome, improving nitric oxide production - and thereby oral and systemic health."
-Dr. Nathan S. Bryan, international expert in nitric oxide biochemistry
Oral Health
How Nitric Oxide Impacts Your Oral Health
This fluoride-free toothpaste is crafted to support a healthy oral microbiome while boosting nitric oxide production - enhancing gum circulation and promoting cardiovascular wellness. Its natural remineralizing properties strengthen enamel, control tartar, and reduce sensitivity. The only toothpaste targeting the nitric oxide microbiome.
Freshens Breath Naturally
Freshens Breath Naturally
Inhibits the growth of cavity-causing bacteria while leaving your mouth fresh and clean.
Boost Blood Flow & Circulation
Boost Blood Flow & Circulation
Helps boost circulation for healthier gums and improved cardiovascular function.
Oral Microbiome Support
Oral Microbiome Support
Nurtures beneficial bacteria for a balanced, resilient oral microbiome.
Supports Gum Health
Supports Gum Health
Promotes blood flow and helps fight harmful bacteria to support healthy gums.
Reduce Plaque Build-up
Reduce Plaque Build-up
Supports healthy saliva pH to neutralize acids and reduce plaque buildup.
Elevates Mood & Energy
Elevates Mood & Energy
Feel more vibrant and energized with the natural boost nitric oxide provides.
Benefits
How To Use
Brush thoroughly at least twice a day, or as directed by your healthcare provider. Apply the desired amount to your toothbrush. For maximum benefit, use daily as consistency yields best results.
Timeline of Benefits
Immediate Use
Enjoy a clean, refreshing brushing experience with a smooth feel and naturally fresh breath.
Within a Few Days
Supports a healthier oral microbiome and balanced saliva pH while helping maintain fresh breath and gum comfort.
Within 2-4 Weeks
Many users notice healthier-looking gums, reduced sensitivity, and a brighter, cleaner smile with consistent daily use.
Long-Term Daily Use
Consistency yields the best results. Over time, daily use helps support long-term oral health, healthy circulation, enamel strength, and overall wellness through nitric oxide support.
Safe for Everyday Use
Formulated with clean, fluoride-free ingredients and designed to be gentle enough for daily use as part of your long-term wellness routine.
* Results can vary from person to person, but many people notice a cleaner, fresher feeling right away, with ongoing benefits becoming more noticeable over time through consistent daily use. Formulated to be safe and gentle for everyday use, this routine works best when used consistently, because long-term wellness and visible results are built through daily habits, not overnight changes.
Watch & Learn
Watch and learn as Susan Shaffer shares how Breath of Life supports the oral microbiome, promotes nitric oxide production, and helps elevate oral and whole-body wellness with a fluoride-free formula.
Susan Shaffer
President and Co-Founder of N1o1 Nitric Oxide
Ingredients
Natural, Powerful Ingredients
Dr. Nathan S. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. With more than 25 years of research in cardiovascular health, his discoveries have shaped the field of nitric oxide therapy and led to product innovations that have improved patient care worldwide.
Hydroxyapatite
Rebuilds and strengthens enamel - a natural, fluoride-free alternative for long-lasting protection.
Hydroxyapatite
Rebuilds and strengthens enamel - a natural, fluoride-free alternative for long-lasting protection.
Potassium Nitrate
Soothes nerve endings to reduce tooth sensitivity.
Potassium Nitrate
Soothes nerve endings to reduce tooth sensitivity.
Zinc Citrate
Helps prevent plaque from hardening into tartar.
Zinc Citrate
Helps prevent plaque from hardening into tartar.
Xylitol & Erythritol
A natural ingredient known for its anti-inflammatory and healing properties, often used to reduce swelling, bruising, and pain.
Xylitol & Erythritol
A natural ingredient known for its anti-inflammatory and healing properties, often used to reduce swelling, bruising, and pain.
Hydrated Silica & Calcium Carbonate
Gently polish teeth to remove surface stains for a brighter smile - without harsh abrasion.
Hydrated Silica & Calcium Carbonate
Gently polish teeth to remove surface stains for a brighter smile - without harsh abrasion.
Essential Oil Blend
Peppermint, spearmint, wintergreen, tea tree, and cinnamon for fresh breath and natural antimicrobial benefit.
Essential Oil Blend
Peppermint, spearmint, wintergreen, tea tree, and cinnamon for fresh breath and natural antimicrobial benefit.
Full Ingredient List
Glycerin, Water, Sorbitol, Hydrated Silica, Calcium Carbonate, Potassium Nitrate, Xylitol, Hydroxyapatite, Mentha Piperita (Peppermint) Oil, Xanthan Gum, Mentha Spicata (Spearmint) Leaf Oil, Gaultheria Procumbens (Wintergreen) Leaf Oil, Menthol, Cocos Nucifera (Coconut) Oil, Zinc Citrate, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Limon (Lemon) Peel Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Cinnamomum Zeylanicum Bark Oil, Eucalyptus Globulus Leaf Oil, Thymus Vulgaris (Thyme) Flower/Leaf Oil, Erythritol, Cellulose Gum, Sodium Lauroyl Sarcosinate.
Full Ingredient List
Glycerin, Water, Sorbitol, Hydrated Silica, Calcium Carbonate, Potassium Nitrate, Xylitol, Hydroxyapatite, Mentha Piperita (Peppermint) Oil, Xanthan Gum, Mentha Spicata (Spearmint) Leaf Oil, Gaultheria Procumbens (Wintergreen) Leaf Oil, Menthol, Cocos Nucifera (Coconut) Oil, Zinc Citrate, Citrus Aurantium Dulcis (Orange) Peel Oil, Citrus Limon (Lemon) Peel Oil, Melaleuca Alternifolia (Tea Tree) Leaf Oil, Cinnamomum Zeylanicum Bark Oil, Eucalyptus Globulus Leaf Oil, Thymus Vulgaris (Thyme) Flower/Leaf Oil, Erythritol, Cellulose Gum, Sodium Lauroyl Sarcosinate.
FAQs
About Dr. Bryan
MEET THE FOUNDER
Dr. Nathan Bryan: A Leading Authority on Nitric Oxide
Dr. Nathan S. Bryan is an international leader in molecular medicine and nitric oxide biochemistry. Dr. Bryan's discoveries have led to product and technology innovations that have improved patient care worldwide.
A Pioneer in Nitric Oxide Science
With over 30 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world's foremost experts on Nitric Oxide's role in human health.
A Pioneer in Nitric Oxide Science
With over 30 years of research in cardiovascular health and molecular medicine, Dr. Bryan is one of the world's foremost experts on Nitric Oxide's role in human health.
Clinically Backed & Scientifically Proven
His discoveries have shaped the field of Nitric Oxide therapy, bringing first to market cutting-edge solutions like the N1o1 Breath of Life Nitric Oxide Boosting Toothpaste you're about to experience.
Clinically Backed & Scientifically Proven
His discoveries have shaped the field of Nitric Oxide therapy, bringing first to market cutting-edge solutions like the N1o1 Breath of Life Nitric Oxide Boosting Toothpaste you're about to experience.
On a Mission to Improve Lives
Dr. Bryan is dedicated to helping people unlock their body's full potential through the power of Nitric Oxide-so they can live longer, healthier, and more vibrant lives.
On a Mission to Improve Lives
Dr. Bryan is dedicated to helping people unlock their body's full potential through the power of Nitric Oxide-so they can live longer, healthier, and more vibrant lives.
Research
[1] Oral Microbiome and Nitric Oxide: the Missing Link in the Management of Blood Pressure
PubMed
Nathan S Bryan, Gena Tribble, Nikola Angelov
Department of Molecular and Human Genetics, Baylor College of Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Department of Periodontics, The University of Texas Health Science Center at Houston, 7000 Fannin, Houston, TX, 77030, USA.
Read The Study
[2] The oral microbiome, nitric oxide and exercise performance
PubMed
Nathan S Bryan, Mia C Burleigh, Chris Easton
Nitric Oxide Innovations, LLC, Houston, TX, USA.
Institute for Clinical Exercise and Health Science, University of the West of Scotland, Blantyre, UK.
Download the PDF
[3] Nathan S. Bryan, PhD, points out how using antiseptic mouthwash can reduce good oral bacteria and cause high blood pressure and other conditions.
Dental Sleep Practice
Nathan S Bryan
Read the Study
[4] Dietary nitrite supplementation protects against myocardial ischemia-reperfusion injury
PubMed
Nathan S Bryan, John W Calvert, John W Elrod, Susheel Gundewar, Sang Yong Ji, David J Lefer
Institute of Molecular Medicine, University of Texas Health Science Center, Houston, TX 77030, USA.
Download the PDF
[5] Effects of sodium nitrite supplementation on vascular function and related small metabolite signatures in middle-aged and older adults
PubMed
Allison E DeVan, Lawrence C Johnson, Forrest A Brooks, Trent D Evans, Jamie N Justice, Charmion Cruickshank-Quinn, Nichole Reisdorph, Nathan S Bryan, Matthew B McQueen, Jessica R Santos-Parker, Michel B Chonchol, Candace J Bassett, Amy L Sindler, Tony Giordano, Douglas R Seals
- Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado
- Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado
- Integrated Department of Immunology, National Jewish Health, Denver, Colorado
- Baylor College of Medicine, Houston, Texas
- Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, Colorado
- TheraVasc, Cleveland, Ohio
[6] Oral nitrite therapy improves vascular function in diabetic mice
PubMed
Amy L Sindler, Kimberly Cox-York, Lauren Reese, Nathan S Bryan, Douglas R Seals, Christopher L Gentile
- Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA Department of Health and Human Physiology, University of Iowa, Iowa City, IA, USA.
- Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA.
- Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA.
- Department of Integrative Physiology, University of Colorado, Boulder, Boulder, CO, USA.
- Department of Food Science and Human Nutrition, Colorado State University, Fort Collins, CO, USA
[7] New Study by Nathan Bryan, PhD., Explains Why the Early Formation of Nitric Oxide in the Mouth by Oral Bacteria Is Essential to Health, Including the Management of Blood Pressure
Newswise
Nathan S Bryan
Read the Article
[8] Nathan S. Bryan, PhD, points out how using antiseptic mouthwash can reduce good oral bacteria and cause high blood pressure and other conditions.
Dental Sleep Practice
Nathan S Bryan
Read the Article
